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References

References of Natural Hormones Replacement Therapy (NHRT) 

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  1. Higher luteal progesterone is associated with low levels of premenstrual aggressive behavior and fatigue. Ziomkiewicz A, Pawlowski B, Ellison PT, Lipson SF, Thune I, Jasienska G. Biol Psychol. 2012 Aug 10;91(3):376-382. doi: 10.1016/j.biopsycho.2012.08.001.

  2. Should the TSH test be utilized in the diagnostic confirmation of suspected hypothyroidism? Wheatland R. Med Hypotheses. 2010 Nov;75(5):458-63. Epub 2010 May 14.

  3. Subclinical Hypothyroidism Is Associated With Increased Risk for All-Cause and Cardiovascular Mortality in Adults. Fen-Yu Tseng, MD, PhD et al. J Am Coll Cardiol. 2012;60(8):730-737. doi:10.1016/j.jacc.2012.03.047

  4. Oxytocin increases trust in humans. Kosfeld M, Heinrichs M, Zak PJ, Fischbacher U, Fehr E. Nature. 2005 Jun 2;435(7042):673-6.

  5. The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans. Macdonald K, Macdonald TM. Harv Rev Psychiatry. 2010;18(1):1-21.

  6. Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type diet. Frassetto LA, Schloetter M, Mietus-Synder M, Morris RC Jr, Sebastian A. Eur J Clin Nutr. 2009 Aug;63(8):947-55. Epub 2009 Feb 11.

NHRT Refe
Mood Enhancement Refe

References of Mood Enhancement & Oxytocin Hormone Deficiency

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  1. Carmichael MS, Warburton VL, Dixen J, Davidson JM. Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity. Arch Sex Behav 1994;23(1):59-79.

  2. Carmichael MS, Warburton VL, Dixen J, Davidson JM. Relationships among cardiovascular, muscular, and oxytocin responses during human sexual activity. Arch Sex Behav 1994;23(1):59-79.

  3. Amico JA, Seif SM, Robinson AG. Oxytocin in human plasma: correlation with neurophysin and stimulation with estrogen. J Clin Endocrinol Metab 1981;52(5):988-993.

  4. Kalin NH, Gibbs DM, Barkskdale CM, Shelton SE, Carnes M. Behavorial Stress Decreases Plasma Oxytocin Concentrations in Primates. Life Sciences 1985;36:1267-1280.

  5. Argiolas A, Gessa GL, Melis MR, Stancampiano R, VACCARI A. Effects of Neonatal and Adult Thyroid Dysfunction on Thymic Oxytocin. Neuroendocrinology 1990;52:556-559.

  6. Evans JJ. Oxytocin in the human–regulation of derivations and destinations. Eur J Endocrinol 1997;137(6):559-571.

  7. Purba JS, Hofman MA, Portegies P, Troost D, Swaab DF. Decreased Number of Oxytocin Neurons in the Paraventricular Nucleus of the Human Hypothalamus in AIDS. Brain 1993;116:795-809.

  8. Oxytocin could be new social-phobic treatment. Health News 2006;12(3):10-11.

  9. Moller A, Hansen BL, Hansen GN, Hagen C. Autoantibodies in sera from patients with multiple sclerosis directed against antigenic determinants in pituitary growth hormone-producing cells and in structures containing vasopressin/oxytocin. J Neuroimmunol 1985;8(2-3):177-184.

  10. Anderberg UM, Uvnas-Moberg K. Plasma oxytocin levels in female fibromyalgia syndrome patients. Z Rheumatol 2000;59(6):373-379.

  11. Evans JJ. Oxytocin in the human–regulation of derivations and destinations. Eur J Endocrinol 1997;137(6):559-571.

  12. van Wimersma Greidanus TB, van de Heijning BJ. Opioid control of vasopressin and oxytocin release. Regul Pept 1993;45(1-2):183-186.

  13. Martin A, State M, Anderson GM et al. Cerebrospinal fluid levels of oxytocin in Prader-Willi syndrome: a preliminary report. Biol Psychiatry 1998;44(12):1349-1352.

  14. Swaab DF. Prader-Willi syndrome and the hypothalamus. Acta Paediatr Suppl 1997;423:50-54.

  15. Swaab DF, Purba JS, Hofman MA. Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases. J Clin Endocrinol Metab 1995;80(2):573-579.

  16. Lucht MJ, Barnow S, Sonnenfeld C et al. Associations between the oxytocin receptor gene (OXTR) and affect, loneliness and intelligence in normal subjects. Prog Neuropsychopharmacol Biol Psychiatry 2009;33(5):860-866.

  17. Scantamburlo G, Hansenne M, Fuchs S et al. Plasma oxytocin levels and anxiety in patients with major depression. Psychoneuroendocrinology 2007;32(4):407-410.

  18. Goldman M, Marlow-O’Connor M, Torres I, Carter CS. Diminished plasma oxytocin in schizophrenic patients with neuroendocrine dysfunction and emotional deficits. Schizophr Res 2008;98(1-3):247-255.

  19. Panksepp J. Commentary on the Possible Role of Oxytocin in Autism. Journal of Autism and Developmental Disorders 1993;23(3):567-569.

  20. Chiodera P, Volpi R, Capretti L et al. Oxytocin response to challenging stimuli in elderly men. Regul Pept 1994;51(2):169-176.

  21. Hofman MA. Lifespan changes in the human hypothalamus. Exp Gerontol 1997;32(4-5):559-575.

  22. Fabian M, Forsling ML, Jones JJ, Lee J. Oxytocin assay with the rat mammary gland in vivo and in vitro. J Physiol 1968;195(2):5P.

  23. Forsling ML, Reinhardt V, Himmler V. Neurohypophysial hormones and prolactin release. J Endocrinol 1974;63(3):579-580.

  24. Kirsch P, Esslinger C, Chen Q et al. Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci 2005;25(49):11489-11493.

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  26. Oxytocin could be new social-phobic treatment. Health News 2006;12(3):10-11.

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  28. Baumgartner T, Heinrichs M, Vonlanthen A, Fischbacher U, Fehr E. Oxytocin shapes the neural circuitry of trust and trust adaptation in humans. Neuron 2008;58(4):639-650.

  29. Mathew SJ, Price RB, Charney DS. Recent advances in the neurobiology of anxiety disorders: implications for novel therapeutics. Am J Med Genet C Semin Med Genet 2008;148C(2):89-98.

  30. Onaka T. Neural pathways controlling central and peripheral oxytocin release during stress. J Neuroendocrinol 2004;16(4):308-312.

  31. Pittman QJ, Spencer SJ. Neurohypophysial peptides: gatekeepers in the amygdala. Trends Endocrinol Metab 2005;16(8):343-344.

  32. Haigh AL, KITCHIN AH, Pickford M. THE EFFECT OF OXYTOCIN ON HAND BLOOD FLOW IN MAN FOLLOWING THE ADMINISTRATION OF AN OESTROGEN AND ISOPRENALINE. J Physiol 1963;169:161-166.

  33. Bouchard F, Paquin J. Skeletal and cardiac myogenesis accompany adipogenesis in P19 embryonal stem cells. Stem Cells Dev 2009;18(7):1023-1032.

  34. Danalache BA, Paquin J, Donghao W et al. Nitric oxide signaling in oxytocin-mediated cardiomyogenesis. Stem Cells 2007;25(3):679-688.

  35. Elabd C, Basillais A, Beaupied H et al. Oxytocin controls differentiation of human mesenchymal stem cells and reverses osteoporosis. Stem Cells 2008;26(9):2399-2407.

  36. Paquin J, Danalache BA, Jankowski M, McCann SM, Gutkowska J. Oxytocin induces differentiation of P19 embryonic stem cells to cardiomyocytes. Proc Natl Acad Sci U S A 2002;99(14):9550-9555.

  37. Cassoni P, Sapino A, Negro F, Bussolati G. Oxytocin inhibits proliferation of human breast cancer cell lines. Virchows Archiv 1994;425:467-472.

  38. Adashi EY, Tucker EM, Hsueh AJ. Direct regulation of rat testicular steroidogenesis by neurohypophysial hormones. Divergent effects on androgen and progestin biosynthesis. J Biol Chem 1984;259(9):5440-5446.

  39. Nicholson HD, Jenkin L. Oxytocin and prostatic function. Adv Exp Med Biol 1995;395:529-538.

  40. Nicholson HD, Guldenaar SE, Boer GJ, Pickering BT. Testicular oxytocin: effects of intratesticular oxytocin in the rat. J Endocrinol 1991;130(2):231-238.

  41. Endocrinology. 2012 May;153(5):2353-61. doi: 10.1210/en.2011-1002. Epub 2012 Mar 20. The ERβ ligand 5α-androstane, 3β,17β-diol (3β-diol) regulates hypothalamic oxytocin (Oxt) gene expression. Sharma D, Handa RJ, Uht RM.

  42. J Neurosci. 2006 Feb 1;26(5):1448-56. The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus. Lund TD, Hinds LR, Handa RJ.

  43. Arturi F, Ferretti E, Presta I et al. Regulation of iodide uptake and sodium/iodide symporter expression in the mcf-7 human breast cancer cell line. J Clin Endocrinol Metab 2005;90(4):2321-2326.

  44. Coiro V, Passeri M, Davoli C et al. Oxytocin Reduces Exercise-Induced ACTH and Cortisol Rise in Man. Acta Endocrinoligial (Copenh) 1988;119:405-412.

  45. Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans. Chen FS, Kumsta R, von Dawans B, Monakhov M, Ebstein RP, Heinrichs M. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):19937-42. doi: 10.1073/pnas.1113079108. Epub 2011 Nov 28.

  46. Topical oxytocin reverses vaginal atrophy in postmenopausal women: a double-blind randomized pilot study. Jonasson AF, Edwall L, Uvnäs-Moberg K. Menopause Int. 2011 Dec;17(4):120-5. doi: 10.1258/mi.2011.011030. Epub 2011 Nov 25.

  47. Helping hands, healthy body? Oxytocin receptor gene and prosocial behavior interact to buffer the association between stress and physical health. Poulin MJ, Holman EA. Horm Behav. 2013 Jan 24. pii: S0018-506X(13)00020-2. doi: 10.1016/j.yhbeh.2013.01.004. [Epub ahead of print]

  48. Kiss A, Mikkelsen JD. Oxytocin–anatomy and functional assignments: a minireview. Endocr Regul 2005;39(3):97-105.

  49. Lippert TH, Mueck AO, Seeger H, Pfaff A. Effects of oxytocin outside pregnancy. Horm Res 2003;60(6):262-271.

  50. Yibchok-Anun S, Hsu WH. Effects of arginine vasopressin and oxytocin on glucagon release from clonal alpha-cell line In-R1-G9: involvement of V1b receptors. Life Sci 1998;63(21):1871-1878.

  51. Lee B, Yang C, Chen TH, al-Azawi N, Hsu WH. Effect of AVP and oxytocin on insulin release: involvement of V1b receptors. Am J Physiol 1995;269(6 Pt 1):E1095-E1100.

  52. Bobbioni-Harsch E, Frutiger S, Hughes G et al. Physiological concentrations of oxytocin powerfully stimulate insulin secretionin vitro. Endocrine 1995;3(1):55-59.

  53. Aging (Albany NY). 2011 Dec;3(12):1169-77. Peripheral oxytocin treatment ameliorates obesity by reducing food intake and visceral fat mass. Maejima Y, Iwasaki Y, Yamahara Y, Kodaira M, Sedbazar U, Yada T.

  54. Argiolas A, Gessa GL, Melis MR, Stancampiano R, VACCARI A. Effects of Neonatal and Adult Thyroid Dysfunction on Thymic Oxytocin. Neuroendocrinology 1990;52:556-559.

  55. Elands J, Resink A, De Kloet ER. Neurohypophyseal Hormone Receptors in the Rat Thymus, Spleen , and Lymphocytes. Endocrinology 1990;126(5):2703-2711.

  56. Geenen V, Legros JJ, Franchimont P, BAUDRIHAYE M, Defresne MP, Boniver J. The Neuroendocrine Thymus: Coexistence of Oxytocin and Neurophysin in the Human Thymus. Science 1986;232:508-511.

  57. Geenen V, CORMANN-GOFFIN N, MARTENS H et al. Thymic neurohypophysial-related peptides and T cell selection. Regulatory Peptides 1993;45:273-278.

  58. MARTENS H, GOXE B, Geenen V. The thymic repertoire of neuroendocrine self-antigens: physiological implications in T-cell life and death. IMMUNOLOGY TODAY 1996;17(7):312-317.

  59. Wiedmeier SE, Araneo BA, Huang K, Daynes RA. Thymic modulation of IL-2 and IL-4 synthesis by peripheral T cells. Cell Immunol 1991;135:501-518.

  60. Hanif K, Goren HJ, Hollenberg MD, Lederis K. Oxytocin Action – Mechanisms for Insulin-Like Activity in Isolated Rat Adipocytes. Molecular Pharmacology 1982;22:381-388.

  61. Suzuki Y, Satoh SI, Kimura M et al. Effects of vasopressin and oxytocin on canine cerebral circulation in vivo. J Neurosurg 1992;77:424-431.

  62. Uryvaev I, Petrov GA. [Decreased pain sensitivity in man after treatment with superlow doses of oxytocin]. Biull Eksp Biol Med 1996;122(11):487-489.

  63. Hiltz RE, Gupta PK, Maher KA et al. Low Threshold of Visceral Nociception and significant Objective Upper Gastrointestinal Pathology in Patients with Fibromyalgia Syndrome. Arthrisis & Rheumatism 1993;36(95):93.

  64. Louvel D, Delvaux M, Felez A et al. Oxytocin increases thresholds of colonic visceral perception in patients with irritable bowel syndrome. Gut 1996;39(5):741-747.

  65. Ohlsson B, Truedsson M, Bengtsson M et al. Effects of long-term treatment with oxytocin in chronic constipation; a double blind, placebo-controlled pilot trial. Neurogastroenterol Motil 2005;17(5):697-704.

  66. Bealer SL, Crowley WR. Stimulation of central and systemic oxytocin release by histamine in the paraventricular hypothalamic nucleus: evidence for an interaction with norepinephrine. Endocrinology 1999;140(3):1158-1164.

  67. Altura BM. Sex and estrogens and responsiveness of terminal arterioles to neurohypophyseal hormones and catecholamines. J Pharmacol Exp Ther 1975;193(2):403-412.

  68. Amico JA, Ervin MG, Leake RD, Fisher DA, Finn FM, Robinson AG. A novel oxytocin-like and vasotocin-like peptide in human plasma after administration of estrogen. J Clin Endocrinol Metab 1985;60(1):5-12.

  69. Fox CA. Recent studies in human coital physiology. Clin Endocrinol Metab 1973;2(3):527-543.

  70. Kroeger M. Oxytocin: key hormone in sexual intercourse, parturition, and lactation. Birth Gaz 1996;13(1):28-30.

  71. Todd K, Lightman SL. Oxytocin release during coitus in male and female rabbits: effect of opiate receptor blockade with naloxone. Psychoneuroendocrinology 1986;11(3):367-371.

  72. Cunningham Jr. ET, Sawchenko PE. Reflex Control of Magnocellular Vasopressin and Oxytocin Secretion. Tins 1991;14:406-411.

  73. Grewen KM, Girdler SS, Amico J, Light KC. Effects of partner support on resting oxytocin, cortisol, norepinephrine, and blood pressure before and after warm partner contact. Psychosom Med 2005;67(4):531-538.

  74. Light KC, Grewen KM, Amico JA. More frequent partner hugs and higher oxytocin levels are linked to lower blood pressure and heart rate in premenopausal women. Biol Psychol 2005;69(1):5-21.

  75. Topical oxytocin reverses vaginal atrophy in postmenopausal women: a double-blind randomized pilot study. Jonasson AF, Edwall L, Uvnäs-Moberg K. Menopause Int. 2011 Dec;17(4):120-5. doi: 10.1258/mi.2011.011030. Epub 2011 Nov 25.

  76. The interaction between the oxytocin and pain modulation in headache patients. Wang YL, Yuan Y, Yang J, Wang CH, Pan YJ, Lu L, Wu YQ, Wang DX, Lv LX, Li RR, Xue L, Wang XH, Bi JW, Liu XF, Qian YN, Deng ZK, Zhang ZJ, Zhai XH, Zhou XJ, Wang GL, Zhai JX, Liu WY. Neuropeptides. 2013 Jan 30. pii: S0143-4179(12)00132-1. doi: 10.1016/j.npep.2012.12.003. [Epub ahead of print]

  77. Topical oxytocin reverses vaginal atrophy in postmenopausal women: a double-blind randomized pilot study. Jonasson AF, Edwall L, Uvnäs-Moberg K. Menopause Int. 2011 Dec;17(4):120-5. doi: 10.1258/mi.2011.011030. Epub 2011 Nov 25.

  78. The interaction between the oxytocin and pain modulation in headache patients. Wang YL, Yuan Y, Yang J, Wang CH, Pan YJ, Lu L, Wu YQ, Wang DX, Lv LX, Li RR, Xue L, Wang XH, Bi JW, Liu XF, Qian YN, Deng ZK, Zhang ZJ, Zhai XH, Zhou XJ, Wang GL, Zhai JX, Liu WY. Neuropeptides. 2013 Jan 30. pii: S0143-4179(12)00132-1. doi: 10.1016/j.npep.2012.12.003. [Epub ahead of print]

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